A Mutation in the Mouse Ttc26 Gene Leads to Impaired Hedgehog Signaling

The phenotype of the spontaneous mutant mouse hop-sterile (hop) is characterized by a hopping gait, polydactyly, hydrocephalus, and male sterility. Previous analyses of the hop mouse revealed a deficiency of inner dynein arms in motile cilia and a lack of sperm flagella, potentially accounting for t...

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Detalles Bibliográficos
Autores principales: Swiderski, Ruth E., Nakano, Yoko, Mullins, Robert F., Seo, Seongjin, Bánfi, Botond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207615/
https://www.ncbi.nlm.nih.gov/pubmed/25340710
http://dx.doi.org/10.1371/journal.pgen.1004689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207615/
https://www.ncbi.nlm.nih.gov/pubmed/25340710
http://dx.doi.org/10.1371/journal.pgen.1004689

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