Cargando…

Keratin 76 Is Required for Tight Junction Function and Maintenance of the Skin Barrier

Keratins are cytoskeletal intermediate filament proteins that are increasingly being recognised for their diverse cellular functions. Here we report the consequences of germ line inactivation of Keratin 76 (Krt76) in mice. Homozygous disruption of this epidermally expressed gene causes neonatal skin...

Descripción completa

Detalles Bibliográficos
Autores principales: DiTommaso, Tia, Cottle, Denny L., Pearson, Helen B., Schlüter, Holger, Kaur, Pritinder, Humbert, Patrick O., Smyth, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207637/
https://www.ncbi.nlm.nih.gov/pubmed/25340345
http://dx.doi.org/10.1371/journal.pgen.1004706