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The Analysis of Mutant Alleles of Different Strength Reveals Multiple Functions of Topoisomerase 2 in Regulation of Drosophila Chromosome Structure

Topoisomerase II is a major component of mitotic chromosomes but its role in the assembly and structural maintenance of chromosomes is rather controversial, as different chromosomal phenotypes have been observed in various organisms and in different studies on the same organism. In contrast to verte...

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Detalles Bibliográficos
Autores principales: Mengoli, Valentina, Bucciarelli, Elisabetta, Lattao, Ramona, Piergentili, Roberto, Gatti, Maurizio, Bonaccorsi, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207652/
https://www.ncbi.nlm.nih.gov/pubmed/25340516
http://dx.doi.org/10.1371/journal.pgen.1004739