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The Analysis of Mutant Alleles of Different Strength Reveals Multiple Functions of Topoisomerase 2 in Regulation of Drosophila Chromosome Structure
Topoisomerase II is a major component of mitotic chromosomes but its role in the assembly and structural maintenance of chromosomes is rather controversial, as different chromosomal phenotypes have been observed in various organisms and in different studies on the same organism. In contrast to verte...
Autores principales: | Mengoli, Valentina, Bucciarelli, Elisabetta, Lattao, Ramona, Piergentili, Roberto, Gatti, Maurizio, Bonaccorsi, Silvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207652/ https://www.ncbi.nlm.nih.gov/pubmed/25340516 http://dx.doi.org/10.1371/journal.pgen.1004739 |
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