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Overexpression of Human GATA-1 and GATA-2 Interferes with Spine Formation and Produces Depressive Behavior in Rats

Functional consequences to which vertebrate GATA transcription factors contribute in the adult brain remain largely an open question. The present study examines how human GATA-1 and GATA-2 (hGATA-1 and hGATA-2) are linked to neuronal differentiation and depressive behaviors in rats. We investigated...

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Detalles Bibliográficos
Autores principales: Choi, Miyeon, Wang, Sung Eun, Ko, Seung Yeon, Kang, Hyo Jung, Chae, Seung Yeun, Lee, Seung Hoon, Kim, Yong-Seok, Duman, Ronald S., Son, Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207676/
https://www.ncbi.nlm.nih.gov/pubmed/25340772
http://dx.doi.org/10.1371/journal.pone.0109253