Dextromethorphan Mediated Bitter Taste Receptor Activation in the Pulmonary Circuit Causes Vasoconstriction

Activation of bitter taste receptors (T2Rs) in human airway smooth muscle cells leads to muscle relaxation and bronchodilation. This finding led to our hypothesis that T2Rs are expressed in human pulmonary artery smooth muscle cells and might be involved in regulating the vascular tone. RT-PCR was p...

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Detalles Bibliográficos
Autores principales: Upadhyaya, Jasbir D., Singh, Nisha, Sikarwar, Anurag S., Chakraborty, Raja, Pydi, Sai P., Bhullar, Rajinder P., Dakshinamurti, Shyamala, Chelikani, Prashen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207743/
https://www.ncbi.nlm.nih.gov/pubmed/25340739
http://dx.doi.org/10.1371/journal.pone.0110373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207743/
https://www.ncbi.nlm.nih.gov/pubmed/25340739
http://dx.doi.org/10.1371/journal.pone.0110373

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