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Functional Dissection of the Clostridium botulinum Type B Hemagglutinin Complex: Identification of the Carbohydrate and E-Cadherin Binding Sites

Botulinum neurotoxin (BoNT) inhibits neurotransmitter release in motor nerve endings, causing botulism, a condition often resulting from ingestion of the toxin or toxin-producing bacteria. BoNTs are always produced as large protein complexes by associating with a non-toxic protein, non-toxic non-hem...

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Detalles Bibliográficos
Autores principales: Sugawara, Yo, Yutani, Masahiro, Amatsu, Sho, Matsumura, Takuhiro, Fujinaga, Yukako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207779/
https://www.ncbi.nlm.nih.gov/pubmed/25340348
http://dx.doi.org/10.1371/journal.pone.0111170