Cargando…

Fc Gamma Receptor IIb on GM-CSF Macrophages Controls Immune Complex Mediated Inhibition of Inflammatory Signals

BACKGROUND: In rheumatoid arthritis (RA) macrophages play a major role in amplifying synovial inflammation. Important activating signals are those induced by Toll-like receptor (TLR) ligands and by activated T cells. The balance between activating and inhibitory Fc gamma receptors (FcγRs) on macroph...

Descripción completa

Detalles Bibliográficos
Autores principales: Santegoets, Kim C. M., Wenink, Mark H., van den Berg, Wim B., Radstake, Timothy R. D. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207781/
https://www.ncbi.nlm.nih.gov/pubmed/25340460
http://dx.doi.org/10.1371/journal.pone.0110966