Efficient Production of sTNFRII-gAD Fusion Protein in Large Quantity by Use of the Modified CHO-S Cell Expression System

TNFα is one of the initial and important mediators to activate downstream signaling pathways by binding to trimerized TNFα receptors (TNFR), and thus is an ideal drug target for cancer therapy. Taking advantage of intrinsic homotimerization of the globular domain of adiponectin (gAD), we have develo...

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Detalles Bibliográficos
Autores principales: Cai, Qinzhen, Zhao, Ai, Yuting Yin, Ma, Lisha, Jiao, Zhenzhen, Zhi, Huilin, Lai, Shouhua, Cheng, Sha, Yang, Hongmei, Lu, Yinxiang, Siminovitch, Katherine A., Gao, Jimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207793/
https://www.ncbi.nlm.nih.gov/pubmed/25340707
http://dx.doi.org/10.1371/journal.pone.0111229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207793/
https://www.ncbi.nlm.nih.gov/pubmed/25340707
http://dx.doi.org/10.1371/journal.pone.0111229

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