Stable Cellular Senescence Is Associated with Persistent DDR Activation

The DNA damage response (DDR) is activated upon DNA damage generation to promote DNA repair and inhibit cell cycle progression in the presence of a lesion. Cellular senescence is a permanent cell cycle arrest characterized by persistent DDR activation. However, some reports suggest that DDR activati...

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Detalles Bibliográficos
Autores principales: Fumagalli, Marzia, Rossiello, Francesca, Mondello, Chiara, d’Adda di Fagagna, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207795/
https://www.ncbi.nlm.nih.gov/pubmed/25340529
http://dx.doi.org/10.1371/journal.pone.0110969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207795/
https://www.ncbi.nlm.nih.gov/pubmed/25340529
http://dx.doi.org/10.1371/journal.pone.0110969

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