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A Novel Function of Human Pumilio Proteins in Cytoplasmic Sensing of Viral Infection

RIG-I-like receptor (RLR) plays a pivotal role in the detection of invading pathogens to initiate type I interferon (IFN) gene transcription. Since aberrant IFN production is harmful, RLR signaling is strictly regulated. However, the regulatory mechanisms are not fully understood. By expression clon...

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Detalles Bibliográficos
Autores principales: Narita, Ryo, Takahasi, Kiyohiro, Murakami, Etsu, Hirano, Emi, Yamamoto, Seiji P., Yoneyama, Mitsutoshi, Kato, Hiroki, Fujita, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207803/
https://www.ncbi.nlm.nih.gov/pubmed/25340845
http://dx.doi.org/10.1371/journal.ppat.1004417