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A Novel Function of Human Pumilio Proteins in Cytoplasmic Sensing of Viral Infection
RIG-I-like receptor (RLR) plays a pivotal role in the detection of invading pathogens to initiate type I interferon (IFN) gene transcription. Since aberrant IFN production is harmful, RLR signaling is strictly regulated. However, the regulatory mechanisms are not fully understood. By expression clon...
Autores principales: | Narita, Ryo, Takahasi, Kiyohiro, Murakami, Etsu, Hirano, Emi, Yamamoto, Seiji P., Yoneyama, Mitsutoshi, Kato, Hiroki, Fujita, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207803/ https://www.ncbi.nlm.nih.gov/pubmed/25340845 http://dx.doi.org/10.1371/journal.ppat.1004417 |
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