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Live Attenuated Francisella novicida Vaccine Protects against Francisella tularensis Pulmonary Challenge in Rats and Non-human Primates

Francisella tularensis causes the disease tularemia. Human pulmonary exposure to the most virulent form, F. tularensis subsp. tularensis (Ftt), leads to high morbidity and mortality, resulting in this bacterium being classified as a potential biothreat agent. However, a closely-related species, F. n...

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Detalles Bibliográficos
Autores principales: Chu, Ping, Cunningham, Aimee L., Yu, Jieh-Juen, Nguyen, Jesse Q., Barker, Jeffrey R., Lyons, C. Rick, Wilder, Julie, Valderas, Michelle, Sherwood, Robert L., Arulanandam, Bernard P., Klose, Karl E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207810/
https://www.ncbi.nlm.nih.gov/pubmed/25340543
http://dx.doi.org/10.1371/journal.ppat.1004439