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Sterol Biosynthesis Is Required for Heat Resistance but Not Extracellular Survival in Leishmania
Sterol biosynthesis is a crucial pathway in eukaryotes leading to the production of cholesterol in animals and various C24-alkyl sterols (ergostane-based sterols) in fungi, plants, and trypanosomatid protozoa. Sterols are important membrane components and precursors for the synthesis of powerful bio...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207814/ https://www.ncbi.nlm.nih.gov/pubmed/25340392 http://dx.doi.org/10.1371/journal.ppat.1004427 |