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Sterol Biosynthesis Is Required for Heat Resistance but Not Extracellular Survival in Leishmania

Sterol biosynthesis is a crucial pathway in eukaryotes leading to the production of cholesterol in animals and various C24-alkyl sterols (ergostane-based sterols) in fungi, plants, and trypanosomatid protozoa. Sterols are important membrane components and precursors for the synthesis of powerful bio...

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Detalles Bibliográficos
Autores principales:	Xu, Wei, Hsu, Fong-Fu, Baykal, Eda, Huang, Juyang, Zhang, Kai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207814/ https://www.ncbi.nlm.nih.gov/pubmed/25340392 http://dx.doi.org/10.1371/journal.ppat.1004427

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