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Therapeutic effect of daphnetin on the autoimmune arthritis through demethylation of proapoptotic genes in synovial cells

BACKGROUND: We have previously reported that dephnetin is therapeutically effective in the treatment of rheumatoid arthritis (RA) in collagen-induced arthritis (CIA) rat model. However, the molecular mechanism and the effect of daphnetin on demethylating proapoptotic genes in the synovial cells rema...

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Detalles Bibliográficos
Autores principales: Shu, Kuanyong, Kuang, Nanzhen, Zhang, Zhiqin, Hu, Ziling, Zhang, Yujuan, Fu, Yingyuan, Min, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207889/
https://www.ncbi.nlm.nih.gov/pubmed/25311560
http://dx.doi.org/10.1186/s12967-014-0287-x