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Antenatal exposure of maternal secondhand smoke (SHS) increases fetal lung expression of RAGE and induces RAGE-mediated pulmonary inflammation

BACKGROUND: Receptors for advanced glycation end-products (RAGE) are immunoglobulin-like pattern recognition receptors abundantly localized to lung epithelium. Our research demonstrated that primary tobacco smoke exposure increases RAGE expression and that RAGE partly mediates pro-inflammatory signa...

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Detalles Bibliográficos
Autores principales: Winden, Duane R, Barton, David B, Betteridge, Bryce C, Bodine, Jared S, Jones, Cameron M, Rogers, Geraldine D, Chavarria, Michael, Wright, Alex J, Jergensen, Zac R, Jimenez, Felix R, Reynolds, Paul R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207891/
https://www.ncbi.nlm.nih.gov/pubmed/25338658
http://dx.doi.org/10.1186/s12931-014-0129-7