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Antenatal exposure of maternal secondhand smoke (SHS) increases fetal lung expression of RAGE and induces RAGE-mediated pulmonary inflammation
BACKGROUND: Receptors for advanced glycation end-products (RAGE) are immunoglobulin-like pattern recognition receptors abundantly localized to lung epithelium. Our research demonstrated that primary tobacco smoke exposure increases RAGE expression and that RAGE partly mediates pro-inflammatory signa...
Autores principales: | Winden, Duane R, Barton, David B, Betteridge, Bryce C, Bodine, Jared S, Jones, Cameron M, Rogers, Geraldine D, Chavarria, Michael, Wright, Alex J, Jergensen, Zac R, Jimenez, Felix R, Reynolds, Paul R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207891/ https://www.ncbi.nlm.nih.gov/pubmed/25338658 http://dx.doi.org/10.1186/s12931-014-0129-7 |
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