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A curated C. difficile strain 630 metabolic network: prediction of essential targets and inhibitors

BACKGROUND: Clostridium difficile is the leading cause of hospital-borne infections occurring when the natural intestinal flora is depleted following antibiotic treatment. Current treatments for Clostridium difficile infections present high relapse rates and new hyper-virulent and multi-resistant st...

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Detalles Bibliográficos
Autores principales: Larocque, Mathieu, Chénard, Thierry, Najmanovich, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207893/
https://www.ncbi.nlm.nih.gov/pubmed/25315994
http://dx.doi.org/10.1186/s12918-014-0117-z