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A curated C. difficile strain 630 metabolic network: prediction of essential targets and inhibitors
BACKGROUND: Clostridium difficile is the leading cause of hospital-borne infections occurring when the natural intestinal flora is depleted following antibiotic treatment. Current treatments for Clostridium difficile infections present high relapse rates and new hyper-virulent and multi-resistant st...
Autores principales: | Larocque, Mathieu, Chénard, Thierry, Najmanovich, Rafael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207893/ https://www.ncbi.nlm.nih.gov/pubmed/25315994 http://dx.doi.org/10.1186/s12918-014-0117-z |
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