5α-Reductase Type 1 Modulates Insulin Sensitivity in Men

CONTEXT: 5α-Reductase (5αR) types 1 and 2 catalyze the A-ring reduction of steroids, including androgens and glucocorticoids. 5α-R inhibitors lower dihydrotestosterone in benign prostatic hyperplasia; finasteride inhibits 5αR2, and dutasteride inhibits both 5αR2 and 5αR1. In rodents, loss of 5αR1 pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Upreti, Rita, Hughes, Katherine A., Livingstone, Dawn E. W., Gray, Calum D., Minns, Fiona C., Macfarlane, David P., Marshall, Ian, Stewart, Laurence H., Walker, Brian R., Andrew, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2014
Materias:
Hot Topics in Translational Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207930/
https://www.ncbi.nlm.nih.gov/pubmed/24823464
http://dx.doi.org/10.1210/jc.2014-1395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207930/
https://www.ncbi.nlm.nih.gov/pubmed/24823464
http://dx.doi.org/10.1210/jc.2014-1395

Ejemplares similares