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Telomerase-Dependent and Independent Telomere Maintenance and its Clinical Implications in Medullary Thyroid Carcinoma

CONTEXT: Telomere maintenance via telomerase activation and the alternative lengthening of telomeres (ALT) mechanism was assessed in medullary thyroid carcinoma. SETTING AND DESIGN: In total, 42 medullary thyroid carcinomas (MTC) were studied including 24 rearranged during transfection (RET)- mutate...

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Detalles Bibliográficos
Autores principales: Wang, Na, Xu, Dawei, Sofiadis, Anastasios, Höög, Anders, Vukojević, Vladana, Bäckdahl, Martin, Zedenius, Jan, Larsson, Catharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207931/
https://www.ncbi.nlm.nih.gov/pubmed/24758186
http://dx.doi.org/10.1210/jc.2014-1158