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Physiological and pathological consequences of cellular senescence

Cellular senescence, a permanent state of cell cycle arrest accompanied by a complex phenotype, is an essential mechanism that limits tumorigenesis and tissue damage. In physiological conditions, senescent cells can be removed by the immune system, facilitating tumor suppression and wound healing. H...

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Detalles Bibliográficos
Autores principales: Burton, Dominick G. A., Krizhanovsky, Valery
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Basel 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207941/
https://www.ncbi.nlm.nih.gov/pubmed/25080110
http://dx.doi.org/10.1007/s00018-014-1691-3