Reptation-Induced Coalescence of Tunnels and Cavities in Escherichia Coli XylE Transporter Conformers Accounts for Facilitated Diffusion

Structural changes and xylose docking to eight conformers of Escherichia Coli XylE, a xylose transporter similar to mammalian passive glucose transporters GLUTs, have been examined. Xylose docks to inward and outward facing conformers at a high affinity central site (K (i) 4–20 µM), previously ident...

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Detalles Bibliográficos
Autores principales: Cunningham, Philip, Naftalin, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207944/
https://www.ncbi.nlm.nih.gov/pubmed/25163893
http://dx.doi.org/10.1007/s00232-014-9711-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207944/
https://www.ncbi.nlm.nih.gov/pubmed/25163893
http://dx.doi.org/10.1007/s00232-014-9711-7

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