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Mouse tetrad analysis provides insights into recombination mechanisms and hotspot evolutionary dynamics

The ability to examine all chromatids from a single meiosis in yeast tetrads has been indispensable for defining mechanisms of homologous recombination initiated by DNA double-strand breaks (DSBs). Using a broadly applicable strategy for the analysis of chromatids from a single meiosis at two recomb...

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Detalles Bibliográficos
Autores principales: Cole, Francesca, Baudat, Frédéric, Grey, Corinne, Keeney, Scott, de Massy, Bernard, Jasin, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207963/
https://www.ncbi.nlm.nih.gov/pubmed/25151354
http://dx.doi.org/10.1038/ng.3068