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Mouse tetrad analysis provides insights into recombination mechanisms and hotspot evolutionary dynamics
The ability to examine all chromatids from a single meiosis in yeast tetrads has been indispensable for defining mechanisms of homologous recombination initiated by DNA double-strand breaks (DSBs). Using a broadly applicable strategy for the analysis of chromatids from a single meiosis at two recomb...
Autores principales: | Cole, Francesca, Baudat, Frédéric, Grey, Corinne, Keeney, Scott, de Massy, Bernard, Jasin, Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207963/ https://www.ncbi.nlm.nih.gov/pubmed/25151354 http://dx.doi.org/10.1038/ng.3068 |
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