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SOX2 is a cancer-specific regulator of tumor initiating potential in cutaneous squamous cell carcinoma

Although the principles that balance stem cell self-renewal and differentiation in normal tissue homeostasis are beginning to emerge, it is still unclear whether cancer cells with tumor initiating potential are similarly governed, or whether they have acquired distinct mechanisms to sustain self-ren...

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Detalles Bibliográficos
Autores principales: Siegle, Jasmin M., Basin, Alice, Sastre-Perona, Ana, Yonekubo, Yoshiya, Brown, Jessie, Sennett, Rachel, Rendl, Michael, Tsirigos, Aristotelis, Carucci, John A., Schober, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207965/
https://www.ncbi.nlm.nih.gov/pubmed/25077433
http://dx.doi.org/10.1038/ncomms5511