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Structural Insights into the Mechanism of Negative Regulation of Single-box High Mobility Group Proteins by the Acidic Tail Domain

The Drosophila and plant (maize) functional counterparts of the abundant vertebrate chromosomal protein HMGB1 (HMG-D and ZmHMGB1, respectively) differ from HMGB1 in having a single HMG box, as well as basic and acidic flanking regions that vary greatly in length and charge. We show that despite thes...

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Detalles Bibliográficos
Autores principales: Stott, Katherine, Watson, Matthew, Bostock, Mark J., Mortensen, Simon A., Travers, Andrew, Grasser, Klaus D., Thomas, Jean O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207994/
https://www.ncbi.nlm.nih.gov/pubmed/25190813
http://dx.doi.org/10.1074/jbc.M114.591115