Recognition of Chelerythrine to Human Telomeric DNA and RNA G-quadruplexes

A study on binding of antitumor chelerythrine to human telomeric DNA/RNA G-quadruplexes was performed by using DNA polymerase stop assay, UV-melting, ESI-TOF-MS, UV-Vis absorption spectrophotometry and fluorescent triazole orange displacement assay. Chelerythrine selectively binds to and stabilizes...

Descripción completa

Detalles Bibliográficos
Autores principales: Bai, Li-Ping, Hagihara, Masaki, Nakatani, Kazuhiko, Jiang, Zhi-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208030/
https://www.ncbi.nlm.nih.gov/pubmed/25341562
http://dx.doi.org/10.1038/srep06767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208030/
https://www.ncbi.nlm.nih.gov/pubmed/25341562
http://dx.doi.org/10.1038/srep06767

Ejemplares similares