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Recognition of Chelerythrine to Human Telomeric DNA and RNA G-quadruplexes

A study on binding of antitumor chelerythrine to human telomeric DNA/RNA G-quadruplexes was performed by using DNA polymerase stop assay, UV-melting, ESI-TOF-MS, UV-Vis absorption spectrophotometry and fluorescent triazole orange displacement assay. Chelerythrine selectively binds to and stabilizes...

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Detalles Bibliográficos
Autores principales:	Bai, Li-Ping, Hagihara, Masaki, Nakatani, Kazuhiko, Jiang, Zhi-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208030/ https://www.ncbi.nlm.nih.gov/pubmed/25341562 http://dx.doi.org/10.1038/srep06767

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