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Gene–environment interaction involved in cholangiocarcinoma in the Thai population: polymorphisms of DNA repair genes, smoking and use of alcohol

OBJECTIVE: Cholangiocarcinoma (CCA) is the most common malignancy in a Northeast Thai population. Smoking and alcohol drinking are associated with the production of free radical intermediates, which can cause several types of DNA lesions. Reduced repair of these DNA lesions would constitute an impor...

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Detalles Bibliográficos
Autores principales: Songserm, Nopparat, Promthet, Supannee, Pientong, Chamsai, Ekalaksananan, Tipaya, Chopjitt, Peechanika, Wiangnon, Surapon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208049/
https://www.ncbi.nlm.nih.gov/pubmed/25335960
http://dx.doi.org/10.1136/bmjopen-2014-005447