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Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminophen-induced acute liver failure

Excessive acetaminophen (APAP) use is one of the most common causes of acute liver failure. Various types of cell death in the damaged liver are linked to APAP-induced hepatotoxicity, and, of these, necrotic cell death of hepatocytes has been shown to be involved in disease pathogenesis. Until recen...

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Detalles Bibliográficos
Autores principales: Takemoto, Kenji, Hatano, Etsuro, Iwaisako, Keiko, Takeiri, Masatoshi, Noma, Naruto, Ohmae, Saori, Toriguchi, Kan, Tanabe, Kazutaka, Tanaka, Hirokazu, Seo, Satoru, Taura, Kojiro, Machida, Keigo, Takeda, Norihiko, Saji, Shigehira, Uemoto, Shinji, Asagiri, Masataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208088/
https://www.ncbi.nlm.nih.gov/pubmed/25349782
http://dx.doi.org/10.1016/j.fob.2014.08.007