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Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminophen-induced acute liver failure
Excessive acetaminophen (APAP) use is one of the most common causes of acute liver failure. Various types of cell death in the damaged liver are linked to APAP-induced hepatotoxicity, and, of these, necrotic cell death of hepatocytes has been shown to be involved in disease pathogenesis. Until recen...
Autores principales: | Takemoto, Kenji, Hatano, Etsuro, Iwaisako, Keiko, Takeiri, Masatoshi, Noma, Naruto, Ohmae, Saori, Toriguchi, Kan, Tanabe, Kazutaka, Tanaka, Hirokazu, Seo, Satoru, Taura, Kojiro, Machida, Keigo, Takeda, Norihiko, Saji, Shigehira, Uemoto, Shinji, Asagiri, Masataka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208088/ https://www.ncbi.nlm.nih.gov/pubmed/25349782 http://dx.doi.org/10.1016/j.fob.2014.08.007 |
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