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Is there a link between proprotein convertase PC7 activity and human lipid homeostasis?
A genome-wide association study suggested that a R504H mutation in the proprotein convertase PC7 is associated with increased circulating levels of HDL and reduced triglycerides in black Africans. Our present results show that PC7 and PC7-R504H exhibit similar processing of transferrin receptor-1, p...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208093/ https://www.ncbi.nlm.nih.gov/pubmed/25349778 http://dx.doi.org/10.1016/j.fob.2014.08.004 |