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Is there a link between proprotein convertase PC7 activity and human lipid homeostasis?
A genome-wide association study suggested that a R504H mutation in the proprotein convertase PC7 is associated with increased circulating levels of HDL and reduced triglycerides in black Africans. Our present results show that PC7 and PC7-R504H exhibit similar processing of transferrin receptor-1, p...
| Autori principali: | , , , |
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| Natura: | Online Articolo testo |
| Lingua: | English |
| Pubblicazione: |
Elsevier
2014
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| Soggetti: | |
| Accesso online: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208093/ https://www.ncbi.nlm.nih.gov/pubmed/25349778 http://dx.doi.org/10.1016/j.fob.2014.08.004 |