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Carbamazepine Prevents Hippocampal Neurodegeneration in Mice Lacking the Neuroprotective Protein, Carboxypetidase E

Carboxypeptidase E (CPE) has recently been described as a neuroprotective protein, and in mice devoid of CPE, a complete loss of the hippocampal CA3 neurons is observed. The pattern of loss is characteristic of that caused by status epilepticus. We therefore set out to determine when this loss occur...

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Detalles Bibliográficos
Autores principales: Woronowicz, Alicja, Cawley, Niamh X, Peng Loh, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208313/
https://www.ncbi.nlm.nih.gov/pubmed/25346878
http://dx.doi.org/10.4172/2167-065X.S1-002