Cargando…

Differential effects of glyoxalase 1 overexpression on diabetic atherosclerosis and renal dysfunction in streptozotocin‐treated, apolipoprotein E‐deficient mice

The reactive dicarbonyls, glyoxal and methylglyoxal (MG), increase in diabetes and may participate in the development of diabetic complications. Glyoxal and MG are detoxified by the sequential activities of glyoxalase 1 (GLO1) and glyoxalase 2. To determine the contribution of these dicarbonyls to t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Geoffrion, Michèle, Du, Xueliang, Irshad, Zehra, Vanderhyden, Barbara C., Courville, Kerri, Sui, Guangzhi, D'Agati, Vivette D., Ott‐Braschi, Sylvie, Rabbani, Naila, Thornalley, Paul J., Brownlee, Michael, Milne, Ross W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wiley Periodicals, Inc. 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208644/ https://www.ncbi.nlm.nih.gov/pubmed/24920125 http://dx.doi.org/10.14814/phy2.12043

Ejemplares similares

Knockdown of Glyoxalase 1 Mimics Diabetic Nephropathy in Nondiabetic Mice
por: Giacco, Ferdinando, et al.
Publicado: (2014)

Emerging Glycation-Based Therapeutics—Glyoxalase 1 Inducers and Glyoxalase 1 Inhibitors
por: Rabbani, Naila, et al.
Publicado: (2022)

Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics
por: Rabbani, Naila, et al.
Publicado: (2016)

Alpha-synuclein deficiency leads to increased glyoxalase I expression and glycation stress
por: Kurz, Alexander, et al.
Publicado: (2010)

Intracellular Accumulation of Methylglyoxal by Glyoxalase 1 Knock Down Alters Collagen Homoeostasis in L6 Myoblasts
por: Stratmann, Bernd, et al.
Publicado: (2017)

Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer
por: Ashour, Amal, et al.
Publicado: (2020)

Glycation of LDL by Methylglyoxal Increases Arterial Atherogenicity: A Possible Contributor to Increased Risk of Cardiovascular Disease in Diabetes
por: Rabbani, Naila, et al.
Publicado: (2011)

IDF21-0230 Anti-inflammatory activity of glyoxalase-1 inducer supports further evaluation for prevention of COVID-19
por: Xue, M., et al.
Publicado: (2022)

Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Spliceosome
por: Alhujaily, Muhanad, et al.
Publicado: (2021)

Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance
por: Thornalley, Paul J., et al.
Publicado: (2010)

Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal
por: Irshad, Zehra, et al.
Publicado: (2019)

In Search of C3G Tissue Biomarkers
por: D’Agati, Vivette D., et al.
Publicado: (2019)

Methylglyoxal and glyoxalase 1—a metabolic stress pathway-linking hyperglycemia to the unfolded protein response and vascular complications of diabetes
por: Rabbani, Naila
Publicado: (2022)

Glyoxalase 1-knockdown in human aortic endothelial cells – effect on the proteome and endothelial function estimates
por: Stratmann, Bernd, et al.
Publicado: (2016)

Innate immunity pathways regulate the nephropathy gene Apolipoprotein L1
por: Nichols, Brendan, et al.
Publicado: (2014)

A Fresh Perspective on Monoclonal Gammopathies of Renal Significance
por: Aucouturier, Pierre, et al.
Publicado: (2021)

De Novo and Relapsing Glomerular Diseases After COVID-19 Vaccination: What Do We Know So Far?
por: Bomback, Andrew S., et al.
Publicado: (2021)

Increased Glycation and Oxidative Damage to Apolipoprotein B100 of LDL Cholesterol in Patients With Type 2 Diabetes and Effect of Metformin
por: Rabbani, Naila, et al.
Publicado: (2010)

Glyoxalase 1 copy number variation in patients with well differentiated gastro-entero-pancreatic neuroendocrine tumours (GEP-NET)
por: Xue, Mingzhan, et al.
Publicado: (2017)

Histologic correlates of gross hematuria following Moderna COVID-19 vaccine in patients with IgA nephropathy
por: Kudose, Satoru, et al.
Publicado: (2021)

Protein glycation – biomarkers of metabolic dysfunction and early-stage decline in health in the era of precision medicine
por: Rabbani, Naila, et al.
Publicado: (2021)

An Introduction to the Special Issue “Protein Glycation in Food, Nutrition, Health and Disease”
por: Rabbani, Naila, et al.
Publicado: (2022)

New developments in the genetics, pathogenesis, and therapy of IgA nephropathy
por: Magistroni, Riccardo, et al.
Publicado: (2015)

Refinement of the HIVAN1 Susceptibility Locus on Chr. 3A1-A3 via Generation of Sub-Congenic Strains
por: Papeta, Natalia, et al.
Publicado: (2016)

Collapsing Glomerulopathy Associated With Hydrophilic Polymer Emboli
por: Kudose, Satoru, et al.
Publicado: (2018)

Atypical Infection-Related Glomerulonephritis With “Masked” IgG-Kappa Crystalline Hump-Like Deposits
por: DiFranza, Lanny T., et al.
Publicado: (2020)

Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease
por: Spanos, Christos, et al.
Publicado: (2018)

Acute kidney injury after hepatic ischemia and reperfusion injury in mice
por: Lee, H. Thomas, et al.
Publicado: (2008)

Unusual Case of Lipoprotein Glomerulopathy First Diagnosed in a Protocol Kidney Allograft Biopsy
por: Batal, Ibrahim, et al.
Publicado: (2018)

Minimal change disease and acute kidney injury following the Pfizer-BioNTech COVID-19 vaccine
por: D’Agati, Vivette D., et al.
Publicado: (2021)

Correction to: Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease
por: Spanos, Christos, et al.
Publicado: (2018)

Acute Tubular Necrosis in a Patient With Myeloma Treated With Carfilzomib
por: Liberman, Vladimir, et al.
Publicado: (2016)

Lysozyme-Induced Nephropathy
por: Santoriello, Dominick, et al.
Publicado: (2016)

Two Cases of Proliferative Glomerulonephritis With Monoclonal IgG Deposits Treated With Renin Angiotensin Inhibition Alone With Long-term Follow-up
por: Rosenstock, Jordan L., et al.
Publicado: (2021)

Mass spectrometric determination of early and advanced glycation in biology
por: Rabbani, Naila, et al.
Publicado: (2016)

Dicarbonyl stress, protein glycation and the unfolded protein response
por: Rabbani, Naila, et al.
Publicado: (2021)

Hexokinase-2-Linked Glycolytic Overload and Unscheduled Glycolysis—Driver of Insulin Resistance and Development of Vascular Complications of Diabetes
por: Rabbani, Naila, et al.
Publicado: (2022)

Glyoxalase Goes Green: The Expanding Roles of Glyoxalase in Plants
por: Sankaranarayanan, Subramanian, et al.
Publicado: (2017)

Protein Glycation in Plants—An Under-Researched Field with Much Still to Discover
por: Rabbani, Naila, et al.
Publicado: (2020)

Light chain cast nephropathy caused by plasmablastic lymphoma of the bladder
por: Jafarizade, Mehrian, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_h6f87gefaojm3enb4rs6klm3bk