Cargando…

Transcriptional Repressor Tbx3 Is Required for the Hormone-Sensing Cell Lineage in Mammary Epithelium

The transcriptional repressor Tbx3 is involved in lineage specification in several tissues during embryonic development. Germ-line mutations in the Tbx3 gene give rise to Ulnar-Mammary Syndrome (comprising reduced breast development) and Tbx3 is required for mammary epithelial cell identity in the e...

Descripción completa

Detalles Bibliográficos
Autores principales: Kunasegaran, Kamini, Ho, Victor, Chang, Ted H-. T., De Silva, Duvini, Bakker, Martijn L., Christoffels, Vincent M., Pietersen, Alexandra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208772/
https://www.ncbi.nlm.nih.gov/pubmed/25343378
http://dx.doi.org/10.1371/journal.pone.0110191