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Transcriptional Repressor Tbx3 Is Required for the Hormone-Sensing Cell Lineage in Mammary Epithelium
The transcriptional repressor Tbx3 is involved in lineage specification in several tissues during embryonic development. Germ-line mutations in the Tbx3 gene give rise to Ulnar-Mammary Syndrome (comprising reduced breast development) and Tbx3 is required for mammary epithelial cell identity in the e...
Autores principales: | Kunasegaran, Kamini, Ho, Victor, Chang, Ted H-. T., De Silva, Duvini, Bakker, Martijn L., Christoffels, Vincent M., Pietersen, Alexandra M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208772/ https://www.ncbi.nlm.nih.gov/pubmed/25343378 http://dx.doi.org/10.1371/journal.pone.0110191 |
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