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Neuropilin-1 Expression Is Induced on Tolerant Self-Reactive CD8(+) T Cells but Is Dispensable for the Tolerant Phenotype
Establishing peripheral CD8(+) T cell tolerance is vital to avoid immune mediated destruction of healthy self-tissues. However, it also poses a major impediment to tumor immunity since tumors are derived from self-tissue and often induce T cell tolerance and dysfunction. Thus, understanding the mech...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208794/ https://www.ncbi.nlm.nih.gov/pubmed/25343644 http://dx.doi.org/10.1371/journal.pone.0110707 |