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Neuropilin-1 Expression Is Induced on Tolerant Self-Reactive CD8(+) T Cells but Is Dispensable for the Tolerant Phenotype

Establishing peripheral CD8(+) T cell tolerance is vital to avoid immune mediated destruction of healthy self-tissues. However, it also poses a major impediment to tumor immunity since tumors are derived from self-tissue and often induce T cell tolerance and dysfunction. Thus, understanding the mech...

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Detalles Bibliográficos
Autores principales: Jackson, Stephanie R., Berrien-Elliott, Melissa, Yuan, Jinyun, Hsueh, Eddy C., Teague, Ryan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208794/
https://www.ncbi.nlm.nih.gov/pubmed/25343644
http://dx.doi.org/10.1371/journal.pone.0110707