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TRAIL-Mediated Apoptosis in Breast Cancer Cells Cultured as 3D Spheroids

TNF-alpha-related-apoptosis-inducing-ligand (TRAIL) has been explored as a therapeutic drug to kill cancer cells. Cancer cells in the circulation are subjected to apoptosis-inducing factors. Despite the presence of these factors, cells are able to extravasate and metastasize. The homotypic and heter...

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Detalles Bibliográficos
Autores principales: Chandrasekaran, Siddarth, Marshall, Jocelyn R., Messing, James A., Hsu, Jong-Wei, King, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208846/
https://www.ncbi.nlm.nih.gov/pubmed/25343626
http://dx.doi.org/10.1371/journal.pone.0111487