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Development of Nanoparticles Incorporating a Novel Liposomal Membrane Destabilization Peptide for Efficient Release of Cargos into Cancer Cells

In anti-cancer therapy mediated by a nanoparticle-based drug delivery system (DDS), overall efficacy depends on the release efficiency of cargos from the nanoparticles in the cancer cells as well as the specificity of delivery to tumor tissue. However, conventional liposome-based DDS have no mechani...

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Detalles Bibliográficos
Autores principales: Itakura, Shoko, Hama, Susumu, Ohgita, Takashi, Kogure, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208851/
https://www.ncbi.nlm.nih.gov/pubmed/25343714
http://dx.doi.org/10.1371/journal.pone.0111181