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Setting-up an In Vitro Model of Rat Blood-brain Barrier (BBB): A Focus on BBB Impermeability and Receptor-mediated Transport

The blood brain barrier (BBB) specifically regulates molecular and cellular flux between the blood and the nervous tissue. Our aim was to develop and characterize a highly reproducible rat syngeneic in vitro model of the BBB using co-cultures of primary rat brain endothelial cells (RBEC) and astrocy...

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Detalles Bibliográficos
Autores principales: Molino, Yves, Jabès, Françoise, Lacassagne, Emmanuelle, Gaudin, Nicolas, Khrestchatisky, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208856/
https://www.ncbi.nlm.nih.gov/pubmed/24998179
http://dx.doi.org/10.3791/51278