Impact of Temporal Variation on Design and Analysis of Mouse Knockout Phenotyping Studies

A significant challenge facing high-throughput phenotyping of in-vivo knockout mice is ensuring phenotype calls are robust and reliable. Central to this problem is selecting an appropriate statistical analysis that models both the experimental design (the workflow and the way control mice are select...

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Detalles Bibliográficos
Autores principales: Karp, Natasha A., Speak, Anneliese O., White, Jacqueline K., Adams, David J., Hrabé de Angelis, Martin, Hérault, Yann, Mott, Richard F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208881/
https://www.ncbi.nlm.nih.gov/pubmed/25343444
http://dx.doi.org/10.1371/journal.pone.0111239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208881/
https://www.ncbi.nlm.nih.gov/pubmed/25343444
http://dx.doi.org/10.1371/journal.pone.0111239

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