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Impact of Temporal Variation on Design and Analysis of Mouse Knockout Phenotyping Studies
A significant challenge facing high-throughput phenotyping of in-vivo knockout mice is ensuring phenotype calls are robust and reliable. Central to this problem is selecting an appropriate statistical analysis that models both the experimental design (the workflow and the way control mice are select...
Autores principales: | Karp, Natasha A., Speak, Anneliese O., White, Jacqueline K., Adams, David J., Hrabé de Angelis, Martin, Hérault, Yann, Mott, Richard F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208881/ https://www.ncbi.nlm.nih.gov/pubmed/25343444 http://dx.doi.org/10.1371/journal.pone.0111239 |
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