Dichotomy in FcγRIIB deficiency and autoimmune-prone SLAM haplotype clarifies the roles of the Fc receptor in development of autoantibodies and glomerulonephritis

BACKGROUND: The significance of a unique inhibitory Fc receptor for IgG, FcγRIIB (RIIB), in the prevention of spontaneous production of autoantibodies remains controversial, due mainly to the fact that the RIIB locus is adjacent to the autoimmune-related SLAM locus harboring the genes coding for sig...

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Detalles Bibliográficos
Autores principales: Kanari, Yasuyoshi, Sugahara–Tobinai, Akiko, Takahashi, Haruka, Inui, Masanori, Nakamura, Akira, Hirose, Sachiko, Takai, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209029/
https://www.ncbi.nlm.nih.gov/pubmed/25339546
http://dx.doi.org/10.1186/s12865-014-0047-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209029/
https://www.ncbi.nlm.nih.gov/pubmed/25339546
http://dx.doi.org/10.1186/s12865-014-0047-y

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