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Collective and Individual Migration following the Epithelial-Mesenchymal Transition

During cancer progression, malignant cells in the tumour invade surrounding tissues. This transformation of adherent cells to a motile phenotype has been associated with the epithelial mesenchymal transition (EMT). Here, we show that EMT-activated cells migrate through micropillar arrays as a collec...

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Detalles Bibliográficos
Autores principales: Wong, Ian Y., Javaid, Sarah, Wong, Elisabeth A., Perk, Sinem, Haber, Daniel A., Toner, Mehmet, Irimia, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209198/
https://www.ncbi.nlm.nih.gov/pubmed/25129619
http://dx.doi.org/10.1038/nmat4062