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Rational design of a structure-switching DNA aptamer for potassium ions
Structure-switching molecules provide a unique means for analyte detection, generating a response to analyte concentration through a binding-specific conformational change between non-binding and binding-competent states. While most ligand-binding molecules are not structure switching by default, ma...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209343/ https://www.ncbi.nlm.nih.gov/pubmed/25352996 http://dx.doi.org/10.1016/j.fob.2014.08.008 |