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Rational design of a structure-switching DNA aptamer for potassium ions

Structure-switching molecules provide a unique means for analyte detection, generating a response to analyte concentration through a binding-specific conformational change between non-binding and binding-competent states. While most ligand-binding molecules are not structure switching by default, ma...

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Detalles Bibliográficos
Autores principales: Catherine, Andrew T., Shishido, Stephanie N., Robbins-Welty, Gregg A., Diegelman-Parente, Amy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209343/
https://www.ncbi.nlm.nih.gov/pubmed/25352996
http://dx.doi.org/10.1016/j.fob.2014.08.008