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Cardiomyocyte-specific deficiency of ketone body metabolism promotes accelerated pathological remodeling

OBJECTIVE: Exploitation of protective metabolic pathways within injured myocardium still remains an unclarified therapeutic target in heart disease. Moreover, while the roles of altered fatty acid and glucose metabolism in the failing heart have been explored, the influence of highly dynamic and nut...

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Detalles Bibliográficos
Autores principales: Schugar, Rebecca C., Moll, Ashley R., André d’Avignon, D., Weinheimer, Carla J., Kovacs, Attila, Crawford, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209361/
https://www.ncbi.nlm.nih.gov/pubmed/25353003
http://dx.doi.org/10.1016/j.molmet.2014.07.010