Targeting cysteine rich C1 domain of Scaffold protein Kinase Suppressor of Ras (KSR) with anthocyanidins and flavonoids – a binding affinity characterization study

Kinase Suppressor of Ras (KSR) is a molecular scaffold that interacts with the core kinase components of the ERK cascade, Raf, MEK, ERK to provide spatial and temporal regulation of Ras-dependent ERK cascade signaling. Interruption of this mechanism can have a high influence in inhibiting the downst...

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Detalles Bibliográficos
Autores principales: Karthik, Dhananjayan, Majumder, Pulak, Palanisamy, Sivanandy, Khairunnisa, Kalathil, Venugopal, Varsha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2014
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209367/
https://www.ncbi.nlm.nih.gov/pubmed/25352726
http://dx.doi.org/10.6026/97320630010580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209367/
https://www.ncbi.nlm.nih.gov/pubmed/25352726
http://dx.doi.org/10.6026/97320630010580

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